- Research shows that children who sleep under double-treated nets are less than half as likely to contract malaria as those who use single-treated nets.
- Experts say the study is evidence that mosquito nets containing two or more pesticides should have been approved for widespread use long ago.
- Mosquitoes have evolved to be resistant to pyrethroids – a class of insecticides the world relies on to prevent malaria
Embargo – 23:30 GMT Tuesday 24 January
A new study on the use of insecticides in anti-mosquito nets has proven that thousands of people have been unnecessarily infected with malaria due to policy failures, according to experts at University College Cork (UCC) in Ireland. rice field.
Writing for authoritative journals lancetProfessor Gerry Killeen, AXA Research Chair for Pathogen Ecology at UCC, said the results of a large-scale trial in which mosquito nets were treated with not just one but two insecticides showed just how big an impact such a combination of active ingredients could have. It states that it clearly shows how to give The extraordinary disease burden caused by malaria in rural Africa.
Professor Killeen was commenting on research in Benin by Manfred Akrombessi and his team. lancet.
Because mosquitoes have evolved to be resistant to pyrethroids (the class of insecticides the world relies on for malaria prevention), children sleeping under mosquito nets treated only with this active ingredient, on average, I get malaria once a year, but my neighbor got sick at half that rate with dual-ingredient nets.
Professor Killeen, who wrote the commentary with Dr Seynabou Sougoufara of Kiel University, said the landmark paper should have been approved for widespread use long before such bed nets containing two or more insecticides were used. He also states that he has proved that he did.
“By using two or more active ingredients, such combination nets can decisively kill insecticide-resistant mosquito subspecies before they can multiply, thus preventing resistance in entire mosquito populations in the first place.” It can prevent it from being established,” Professor Killeen commented.
“Importantly, pyrethroids are highly useful insecticides for public health purposes. Besides being a standard treatment for mosquito nets, they are the only insecticides that can be safely disseminated into the air as repellent vapors. It is also a class and protects people suffering from malaria areas when they are awake and operating outside the protection of mosquito nets.
“It is unknown at this time if we can reverse the pyrethroid-resistant genie, but that is exactly why the ongoing research in collaboration with the Ifakara Health Research Institute and the Sokoine University of Agriculture in Tanzania is so important.” said Professor Killeen.
“Looking to the future, with the hope that new pesticide combinations can be used to reselect pyrethroid susceptibility traits that make it easier for people to protect against mosquitoes and malaria, our team is currently conducting research in southern Tanzania. We are investigating wildlife reserves for malaria-carrying mosquitoes that eat wild animals rather than humans or livestock to escape the pressure of pesticides,” he said.
Getting ahead of insecticide-resistant malaria-carrying mosquitoes
Article publication date
January 24, 2023
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