Monkeypox outbreaks associated with human-to-

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Image: Monkeypox requires special attention given its worldwide spread.
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Credits: Monstera, Pexels (CC0, https://creativecommons.org/publicdomain/zero/1.0/)

Since May 2022, monkeypox cases have increased globally, raising fears of a new pandemic.Research published in open access journals PLOS pathogen September 22ndnd A paper by Professor Souha Kanj, American University of Beirut Medical Center, Beirut, Lebanon, and colleagues comprehensively describes its clinical features, risk factors, infection control and prevention measures, and potential treatments. .

Historically, monkeypox was primarily confined to endemic areas of western and central Africa and was transmitted through contact with infected animals. However, human-to-human transmission has recently become the main route of transmission, raising concerns about its spread in previously undetected areas. To better understand the epidemiological context of this new outbreak, the authors conducted a literature review of the available evidence on monkeypox. They found that confirmed, probable and/or probable monkeypox cases increased tenfold in more than 76 countries during the current outbreak. It suggests an increase in disease incidence and the potential for improved surveillance. The current cases demonstrate rapid human-to-human transmission and are not necessarily linked to travel to endemic areas of Africa, raising concerns of rapid community spread.

The literature review has several limitations, including the small sample size of case studies and the lack of randomized controlled trials of monkeypox treatment, both of which limit generalization. Larger and more robust studies are needed to determine not only the extent of the current outbreak, but also specific risk factors, modes of transmission and potential treatments.

According to the authors, “Important gaps in information need further study to get better answers, such as the exact mode of transmission and the role of animal reservoirs. Physicians should also keep atypical symptoms in mind and guide patients based on WHO and CDC criteria to avoid outbreaks. We need to help contain it.”

“Monkeypox has been declared a public health emergency, requiring special attention and early diagnosis, given its widespread and atypical manifestations worldwide,” Kanj and co-authors said. ”

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In your reporting, use this URL to provide access to the article, which is freely available. PLOS pathogen: http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1010768

Quote: El Eid R, Allaw F, Haddad SF, Kanj SS (2022) Human monkeypox: a review of the literature. PLoS Pathog 18(9): e1010768. https://doi.org/10.1371/journal.ppat.1010768

author’s country: Lebanon

Funding: The authors received no specific funding for this manuscript.


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